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Colorant

CI 45220

CAS 5873-16-5 Updated
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

CI 45220 — a halogenated xanthene (fluorescein-family) pink/red colorant permitted under EU Annex IV. Mid-orange because the class shows phototoxicity and sensitisation flags that require strict use conditions.

Skin benefits

  • Provides pink/red xanthene coloration in cosmetics under regulated use

Known concerns

  • Halogenated xanthene with phototoxicity potential
  • EU Annex IV restrictions and labelling requirements
  • Skin sensitisation reports in fluorescein derivative class

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.