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CINNAMALDEHYDE DIMETHYL ACETAL

CAS 4364-06-1
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An acetal derived from cinnamaldehyde that shares structural alerts for skin sensitization despite acetal modification.

Cinnamaldehyde dimethyl acetal is structurally related to cinnamaldehyde, a well-documented skin sensitizer. While acetal formation can reduce direct reactivity, metabolic hydrolysis may regenerate cinnamaldehyde on skin. Not currently restricted under EU cosmetics law, but the structural alert warrants caution in leave-on products for sensitive skin.

Skin benefits

  • Fragrance material with spicy, cinnamon-like notes

Known concerns

  • Potential skin sensitization (structural analogue to cinnamaldehyde)
  • May hydrolyze to cinnamaldehyde on skin

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.