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CIS-3-HEXENYL PHENYLACETATE

CAS 42436-07-7
76

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An ester of cis-3-hexenol with phenylacetic acid providing a sweet, honey-like, floral-green fragrance profile. The phenylacetate substructure introduces mild allergenic potential that requires attention in formulation.

Cis-3-hexenyl phenylacetate combines the green-note character of cis-3-hexenol with the sweet, honey-like aroma of phenylacetic acid. Phenylacetic acid and its esters are listed as fragrance allergens in EU Regulation 1223/2009 Annex III under the broader phenyl methyl framework, and ingredients containing phenylacetate groups may require allergen declaration on product labels above 0.001% in leave-on products. The compound is otherwise considered safe by IFRA within recommended concentration limits.

Skin benefits

  • Fragrance material; no documented direct skin conditioning benefit

Known concerns

  • May require EU fragrance allergen labeling (phenylacetate group)
  • IFRA restrictions apply
  • Potential for sensitization in susceptible individuals

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.