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clonitazene

CAS 3861-76-5
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Clonitazene is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Clonitazene is a synthetic opioid belonging to the benzimidazole opioid series, with analgesic potency comparable to morphine but with faster onset. It was developed as a potent analgesic but was placed under international control due to its high abuse potential and risk of respiratory depression. The EU Commission has not included clonitazene in any cosmetic-authorized list; as a scheduled controlled substance with CNS depressant activity, it is incompatible with cosmetic product safety requirements.

Known concerns

  • Potent synthetic opioid with high abuse liability
  • CNS depressant – risk of respiratory depression
  • Internationally controlled substance (Schedule I)
  • No cosmetic use authorized in EU

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.