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COUMAROYL METHOXYTRYPTAMINE

CAS 366452-03-1
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Coumaroyl Methoxytryptamine is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

COUMAROYL METHOXYTRYPTAMINE is a hydroxycinnamic acid amide with a methoxy-tryptamine moiety. It is related to natural plant compounds found in various species. The coumaroyl (p-coumaric acid) portion suggests good tolerance, while the methoxytryptamine portion indicates pharmacological activity as a serotonin receptor modulator, which raises concerns for cosmetic use. No EU cosmetic restrictions identified, but the compound's pharmacological activity warrants caution.

Skin benefits

  • Antioxidant properties from coumaric acid moiety

Known concerns

  • Serotonin receptor activity
  • Potential pharmacological effects on skin
  • Limited safety data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.