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Coumetarol (INN)

CAS 4366-18-1
10

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Coumetarol (inn) is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Coumetarol (also known as coumachlor) is an anticoagulant rodenticide functioning as a vitamin K epoxide reductase inhibitor. Its mechanism of action makes it highly toxic if absorbed systemically, and it has no established role in cosmetic formulations. While not specifically listed on EU cosmetic Annexes, the hazard profile (anticoagulant rodendicide) effectively prohibits its use in cosmetics and justifies a very low safety score.

Known concerns

  • Anticoagulant rodenticide mechanism of action
  • Vitamin K antagonist — systemic toxicity risk
  • No authorised cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.