Skin Conditioning
CYANOCOBALAMIN/YEAST POLYPEPTIDE
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A conjugate of vitamin B12 (cyanocobalamin) with a yeast-derived polypeptide, used for skin conditioning. Generally mild; yeast-allergic users should be aware.
Cyanocobalamin/Yeast Polypeptide is a cosmetic ingredient consisting of vitamin B12 (cyanocobalamin) complexed or coupled with a polypeptide fraction obtained from yeast (typically Saccharomyces) fermentation. It is supplied as a skin-conditioning active. Cyanocobalamin itself is the synthetic shelf-stable form of vitamin B12 and is generally well tolerated topically; yeast-derived polypeptides bring a mix of amino acids and small peptides. There is no CIR or SCCS opinion specific to this combination and no GHS classification. Yeast-derived materials are variable in composition between suppliers and can occasionally trigger reactions in users with strong yeast sensitivities. Use levels are low and irritation potential is low.
Function
Skin benefits
- Vitamin B12 content
- Yeast peptide skin conditioning
- Mild surface hydration
Known concerns
- Yeast-allergen potential
- Variable supplier composition
- No specific regulatory monograph
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.