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Cyclarbamate (INN)

CAS 5779-54-4
15

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Cyclarbamate (inn) is a cosmetic ingredient. Exercise caution due to limited available safety data.

Cyclarbamate is a carbamate tranquilizer and muscle relaxant drug with anxiolytic and sedative properties. It acts on the central nervous system via GABAergic mechanisms. The EU Cosmetics Regulation Annex III restricts its use at ≥0.1% in cosmetic products. Its pharmacological profile (CNS depression, muscle relaxation) is incompatible with cosmetic use, and systemic absorption from topical application could produce unwanted CNS effects.

Known concerns

  • CNS depressant activity
  • Muscle relaxant properties
  • Anxiolytic pharmacological effect
  • Restricted to ≤0.1% in EU cosmetics

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.