Skip to content

Chelating Agent

CYCLO PEG-6

CAS 17455-13-9
50

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

18-crown-6, a cyclic polyether that traps potassium ions. Useful as a chemical tool but not a benign humectant — animal data show real systemic toxicity, so cosmetic use should be very limited and well-justified.

Function

NOT REPORTED

Skin benefits

  • Chelates cations to stabilize sensitive actives
  • Can improve solubility of certain salts
  • Niche use in specialty formulations

Known concerns

  • Strong potassium ion binding linked to systemic toxicity in animal studies
  • Acute oral toxicity reported for crown ethers
  • Not a typical cosmetic-grade humectant; very limited cosmetic safety review

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related chelating agents

50
PYRICARBATE
Chelating Agent
 48
PHOSPHONOBUTANETRICARBOXYLIC ACID
Chelating Agent
 55
DISODIUM ALUMINATE GLUCARATE/GLUCONATE/GLYCOLATE/TARTRATE/OXALATE
Chelating Agent
 55
LAURYL ALCOHOL DIPHOSPHONIC ACID
Chelating Agent
 55
POTASSIUM EDTA-PLATINUM
Chelating Agent
 55
SODIUM PENTAERYTHRITYL HYDROXYPROPYL IMINODIACETATE DENDRIMER
Chelating Agent
 55
SODIUM PHOSPHONO-PYRIDOXYLIDENERHODANINE
Chelating Agent
 58
AMINOTRIMETHYLENE PHOSPHONIC ACID
Chelating Agent

Check your shelf

Find CYCLO PEG-6 in your products.

Scan any cosmetic product with LuxSense to see if it contains CYCLO PEG-6 and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.