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Skin Conditioning

CYCLO S-KINOSHITA'S CONE OLIGOPEPTIDE-1 AMIDE

70

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A cyclised version of a marine-derived signal peptide engineered for greater protease resistance, giving longer-lasting skin matrix support. Cyclic structure raises minor questions on immunogenic potential.

Function

SKIN PROTECTINGSKIN CONDITIONING - MISCELLANEOUS

Skin benefits

  • Cyclic structure resists proteolysis
  • Longer-lasting matrix support
  • Skin conditioning
  • No EU Annex listings

Known concerns

  • Cyclic peptide structure raises minor immunogenic potential questions
  • Marine-derived (cone snail) parent — origin should be checked for sensitisers
  • Limited public toxicology data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.