Skin Conditioning
CYCLO S-KINOSHITA'S CONE OLIGOPEPTIDE-1 AMIDE
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A cyclised version of a marine-derived signal peptide engineered for greater protease resistance, giving longer-lasting skin matrix support. Cyclic structure raises minor questions on immunogenic potential.
Function
Skin benefits
- Cyclic structure resists proteolysis
- Longer-lasting matrix support
- Skin conditioning
- No EU Annex listings
Known concerns
- Cyclic peptide structure raises minor immunogenic potential questions
- Marine-derived (cone snail) parent — origin should be checked for sensitisers
- Limited public toxicology data
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.