Skin Conditioning
CYCLOHEXAPEPTIDE-90
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A cyclic six-amino-acid peptide used as a skin-conditioning agent. Cyclization improves on-skin stability; independent safety/efficacy data are limited.
Cyclohexapeptide-90 is a head-to-tail cyclized six-residue peptide for cosmetic skin-conditioning use. Cyclic peptides resist exopeptidase degradation, giving longer functional residence on skin than linear peptides. Used at parts-per-million levels in serums and creams. No independent CIR or SCCS review of this specific INCI is available; efficacy claims rely on supplier studies. Listed in EU CosIng. Conservative classification is yellow with low evidence.
Function
Skin benefits
- Improved on-skin stability via cyclization
- Trace-level skin conditioning
- Low sensitization potential
Known concerns
- Limited independent safety data
- No CIR/SCCS monograph
- Efficacy claims supplier-driven
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.