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Active / Depigmenting

CYSTEAMINE

CAS 60-23-1
50

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Aminothiol active used in depigmenting products as an alternative to hydroquinone. Shows clinical benefit for melasma, but causes strong odor, stinging, and possible irritation, so formulation matters.

Skin benefits

  • Tyrosinase pathway modulator used for hyperpigmentation
  • Alternative to hydroquinone in some depigmenting products
  • Clinical studies support efficacy for melasma at controlled levels

Known concerns

  • Strong sulfur odor and irritation potential
  • Can cause redness, stinging, and contact dermatitis
  • Stability and oxidation issues require careful formulation
  • Not on EU positive cosmetic actives list, regulatory status varies

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.