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Deanol aceglumate (INN)

CAS 3342-61-8
20

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Deanol Aceglumate (inn) is a cosmetic ingredient. Exercise caution due to limited available safety data.

Deanol aceglumate (deanotate) is the salt of 2-dimethylaminoethanol (deanol) with aceglutamic acid, used as a nootropic and CNS-active pharmaceutical agent. Deanol is a choline precursor that crosses the blood-brain barrier and is converted to acetylcholine. EU Annex III restricts deanol aceglumate at ≥0.1% in cosmetic products, reflecting concerns about its pharmacological activity on the central nervous system and potential for systemic effects from topical application.

Known concerns

  • CNS-active pharmacological compound
  • Cholinergic activity
  • Systemic effects from skin absorption
  • Restricted to ≤0.1% in EU cosmetics

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.