Other
Dicoumarol (INN)
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Dicoumarol (inn) is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.
Dicoumarol is a natural coumarin-derived anticoagulant originally identified as the hemorrhagic agent in spoiled sweet clover silage. Like phenprocoumon, it acts as a vitamin K epoxide reductase inhibitor, disrupting blood clotting. Under EU CosIng, anticoagulant compounds used as rodenticides are explicitly banned as cosmetic ingredients — they have no cosmetic utility and present severe systemic toxicity risk from dermal absorption. The compound appears in Annex II as a prohibited substance with no established safe cosmetic use.
Known concerns
- Potent anticoagulant — severe bleeding risk from dermal exposure
- Annex II prohibited — no cosmetic use permitted
- Vitamin K antagonist mechanism with systemic toxicity
- CMR classification for anticoagulant rodenticides
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.