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DIETHYL ITACONATE

CAS 2409-52-1
52

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Diethyl Itaconate is a cosmetic ingredient. Exercise caution due to limited available safety data.

Diethyl itaconate is the diethyl ester of itaconic acid (a naturally occurring dicarboxylic acid). It carries GHS hazard warnings for skin irritation (H315), eye irritation (H319), and potential respiratory sensitization. At cosmetic use levels in finished formulations, these hazards are typically mitigated. The compound is not specifically listed in EU Annex II or III, though irritation potential requires careful concentration control.

Skin benefits

  • May function as a plasticizing agent
  • Solvent properties

Known concerns

  • Skin irritation (H315)
  • Eye irritation (H319)
  • Potential respiratory irritation
  • Must be used below irritation thresholds

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.