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Emollient

DIHEXYL ADIPATE

CAS 110-33-8
84

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A medium-chain diester (hexanol + adipic acid) used as a light, silky emollient and solvent for sunscreen actives.

Dihexyl adipate (CAS 110-33-8) is the dihexyl ester of adipic acid, a low-viscosity emollient that solubilizes UV filters and other lipophilic actives while contributing a dry, smooth finish. CIR has reviewed dialkyl adipate esters as safe for cosmetic use. No CMR, endocrine, or significant GHS hazards reported; well-tolerated on skin at typical use levels (1-15%) and broadly used in sunscreens, lotions, and color cosmetics.

Function

SKIN CONDITIONING - EMOLLIENT, SKIN CONDITIONING, SOLVENT

Skin benefits

  • Lightweight, fast-absorbing slip
  • Solubilizes UV filters
  • Reduces stickiness in oil phases

Known concerns

  • Possible mild irritation at very high levels
  • Moderate compound-specific clinical data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related emollients

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.