Pigmentation modulator
DIHYDROXYINDOLE
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
Dihydroxyindole is a reactive indole used in pigmentation and self-tanning research. It oxidizes readily and lacks robust cosmetic safety review, warranting caution for routine consumer use.
Function
Skin benefits
- Indole derivative that can act as a melanin precursor
- Investigated for self-tanning and pigmentation applications
- May offer antioxidant activity
Known concerns
- Limited cosmetic safety review
- Potential skin staining and uneven pigmentation
- Reactive intermediate prone to oxidation and impurities
- Structural concerns regarding genotoxic potential of indole derivatives
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.