Other
DIHYDROXYMETHOXYCHALCONE
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Dihydroxymethoxychalcone is a cosmetic ingredient used in product formulations. Note: classified as harmful to aquatic environments. Exercise caution due to limited available safety data.
Dihydroxymethoxychalcone is a polyphenolic chalcone structure with preliminary in vitro data suggesting tyrosinase-inhibitory (skin-lightening) activity. It is not listed in EU cosmetic restriction Annexes, but its safety profile in topical applications is insufficiently documented by industry databases. Use in leave-on products should be approached with caution given limited sensitization data for novel chalcones.
Skin benefits
- Preliminary tyrosinase inhibition suggests skin-lightening potential
- Antioxidant activity from polyphenolic structure
Known concerns
- Limited clinical safety data for topical use
- Potential for cross-reactivity with other chalcones
- Insufficient long-term sensitization data
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related others
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.