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DIMETHYL-3-CYCLOHEXENE-1-CARBALDEHYDE

CAS 27939-60-2
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A dimethylcyclohexene carbaldehyde with both irritant and sensitization potential, used as a fragrance ingredient. The combined H317 (sensitization), H319 (eye), and environmental toxicity classifications indicate a challenging safety profile.

Dimethyl-3-Cyclohexene-1-Carbaldehyde is a cyclohexene carbaldehyde with gem-dimethyl substitution. The alpha,beta-unsaturated aldehyde structure (the formyl group is conjugated with the double bond) creates significant electrophilic reactivity. The H317 classification indicates skin sensitization, H315/H319 indicate irritation, and H411/H412 indicate aquatic toxicity. It is listed in EU Annex III of the Cosmetics Regulation as a fragrance allergen subject to declaration requirements when present above 0.001% in leave-on products or 0.01% in rinse-off products.

Skin benefits

  • Fragrance ingredient with fresh, citrus, and herbal notes

Known concerns

  • Skin sensitizer (H317)
  • Skin and eye irritant (H315, H319)
  • EU Annex III fragrance allergen requiring declaration
  • Aquatic toxicity (H411, H412)
  • Alpha,beta-unsaturated aldehyde with high reactivity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.