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DIMETHYL ISOPROPANOLAMINE

CAS 108-16-7
40

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An alkanolamine used as a pH adjuster and emulsifying agent in cosmetic formulations, but subject to restrictions due to secondary amine concerns. The IFRA has set specific limits on its use.

Dimethyl isopropanolamine (DMIPA) is an alkanolamine used as a pH adjuster and emulsifying agent in cosmetic formulations. As a secondary amine, it has been subject to scrutiny regarding nitrosamine formation potential, and IFRA has set specific guidelines limiting its use. The EU Cosmetics Regulation does not specifically list it in restriction annexes, but formulations must ensure no nitrosamine formation occurs.

Skin benefits

  • pH adjuster helping maintain product stability
  • Emulsifying properties aid formulation consistency

Known concerns

  • Secondary amine with potential nitrosamine formation concern
  • IFRA restrictions limit use in certain product categories
  • Skin and eye irritation potential at high concentrations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.