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Solvent

DIMETHYL ISOSORBIDE

CAS 5306-85-4 Updated
78

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A sugar-derived solvent (DMI) — helps deliver actives like vitamin C deeper into skin. Generally well tolerated; remember it can boost both helpful and harmful ingredients.

Skin benefits

  • Solvent for actives
  • Boosts penetration of vitamins and antioxidants
  • Plant-derived (corn)
  • Improves formulation feel

Known concerns

  • Penetration enhancement also boosts other ingredients
  • Limited human dermal dossier

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

PC

PubChem

U.S. NIH compound data, GHS hazard codes and toxicity literature.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.