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DIMETHYL KETOGLUTARATE

78

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Dimethyl Ketoglutarate is a cosmetic ingredient. Exercise caution due to limited available safety data.

Dimethyl ketoglutarate is the dimethyl ester of 2-oxoglutaric acid (alpha-ketoglutaric acid), a naturally occurring metabolite in the Krebs cycle. It is used in cosmetics as an emollient and skin-conditioning agent. The compound has a favourable safety profile with no reported sensitization at cosmetic use levels. No EU restrictions apply under current cosmetic regulation.

Skin benefits

  • Emollient properties improve skin softness
  • Skin conditioning agent
  • May support barrier function

Known concerns

  • Minor skin irritation possible at high concentrations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.