DIOSGENIN
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A steroidal saponin from yam with anti-inflammatory effects, subject to EU Annex II/260 restriction conditions.
Diosgenin is a steroidal sapogenin from yam (Dioscorea species) used in cosmetics for its anti-inflammatory and skin-barrier-enhancing properties, listed in EU Annex II/260 of Cosmetics Regulation 1223/2009 with specific restriction conditions. Some evidence suggests mild endocrine activity contributing to its regulatory review. Formulators must verify compliance with the specific restriction conditions applicable to this ingredient.
Skin benefits
- Plant-derived saponin with anti-inflammatory properties
- Used in anti-aging and skin-reshaping formulations
Known concerns
- EU Annex II/260 restricted - specific regulatory conditions apply
- Endocrine activity suggested in literature
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.