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solvent/fragrance

DIOXOLANE

CAS 646-06-0
40

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A small cyclic acetal solvent more common in industrial chemistry than cosmetics; raises concerns about irritation and possible carcinogenicity, with limited dedicated safety review for skincare use.

Function

SOLVENT

Skin benefits

  • Functions as a solvent or fragrance component
  • Provides volatility and aroma diffusion

Known concerns

  • 1,3-Dioxolane is classified as flammable and a Category 2 carcinogen suspicion in some CLP harmonized entries
  • Eye and respiratory irritant in vapor form
  • Limited cosmetic-specific safety review; mainly an industrial solvent
  • Possible peroxide formation on storage

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.