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Skin Conditioning

DIPEPTIDE DIAMINOBUTYROYL BENZYLAMIDE DIACETATE OLIGOPEPTIDE-133

60

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A blend that includes the SYN-AKE-style dipeptide diaminobutyroyl benzylamide diacetate together with an oligopeptide. Plausibly mild; data is limited.

This INCI is a multi-component supplied blend consisting of Dipeptide Diaminobutyroyl Benzylamide Diacetate (the actives ingredient marketed as SYN-AKE — a synthetic mimic of a snake-venom peptide motif used in cosmetics for visible expression-line softening) together with an undefined Oligopeptide-133. The dipeptide component is widely used at parts-per-million levels with no CIR opinion but a relatively benign supplier safety record over more than a decade of cosmetic use. The oligopeptide-133 component is a generic numbered peptide with sparse public data. There is no GHS classification for the blend and no SCCS monograph. Skin penetration of intact peptides is minimal and irritation at use levels is low. Risk in practice is formulation-dependent.

Function

SKIN CONDITIONING

Skin benefits

  • Skin conditioning
  • Marketed expression-line softening
  • Low irritation potential at use levels

Known concerns

  • No regulatory monograph
  • Multi-component blend complicates safety review
  • Sparse independent data on the oligopeptide component

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.