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diphenoxylate

CAS 915-30-0
4

Safety score Β· 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Diphenoxylate is a synthetic opioid used medically (with atropine) for diarrhoea control β€” a pharmaceutical and controlled substance, not a cosmetic ingredient. Any cosmetic listing here is non-compliant with EU rules.

Skin benefits

  • No legitimate cosmetic benefit β€” pharmaceutical anti-diarrhoeal opioid

Known concerns

  • Synthetic opioid (related to meperidine) β€” controlled substance
  • EU Annex II prohibits pharmaceutical actives in cosmetic products
  • No safe topical use scenario

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.