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Speculative active

DIPHENYL ACETAMIDOTRICHLOROETHYL FLUORONITROPHENYL THIOUREA

CAS -
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

An exotic synthetic molecule originally studied as a DNA-damage modulator before that work was retracted. Its halogenated thiourea structure and absence of cosmetic safety review keep it firmly in red.

Function

SKIN PROTECTING

Skin benefits

  • Marketed as a skin-protective and anti-aging ingredient
  • Originally explored as a DNA-damage response modulator (CGK733)

Known concerns

  • Original research on this molecule (CGK733) was retracted for irregularities
  • Contains halogenated thiourea and nitrophenyl groups associated with toxicity
  • Thioureas are known skin sensitisers as a class
  • No SCCS or CIR safety review on this exotic molecule
  • Highly speculative use in cosmetics

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.