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Skin Conditioning

DIPOTASSIUM BRYONOLYL SUCCINATE

CAS -
70

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A potassium salt of a bryonolic-acid succinate ester from Bryonia (Cucurbitaceae plants). Marketed for skin soothing; data is limited.

Dipotassium bryonolyl succinate is the dipotassium salt of bryonolic acid (a pentacyclic triterpene found in Bryonia and other Cucurbitaceae) esterified with succinic acid. The succinate/potassium modifications make a water-dispersible active marketed for anti-inflammatory and skin-soothing claims. Bryonolic acid has shown anti-inflammatory activity in pre-clinical studies. Important caveat: raw Bryonia plants contain bitter cucurbitacin compounds known to cause skin/mucosal irritation, so supplier purification of bryonolic acid from cucurbitacins is critical. There is no CIR or SCCS-specific review; safety data are mostly proprietary.

Function

SKIN CONDITIONING - EMOLLIENT

Skin benefits

  • Marketed for anti-inflammatory action
  • Water-dispersible active
  • Soothing claim

Known concerns

  • Cucurbitacin contamination if poorly purified
  • Limited public toxicology
  • Novel ingredient with thin clinical record

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.