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Vitamin C derivative

DISODIUM ISOSTEARYL ASCORBYL PHOSPHATE

CAS -
78

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

An oil-friendly vitamin C derivative that converts to active vitamin C in the skin. Lab studies link it to collagen support and a brighter complexion, with good tolerability at typical use levels.

Skin benefits

  • Stable, oil-soluble vitamin C derivative that releases ascorbic acid in skin
  • Stimulates collagen synthesis and inhibits MMP-1 in human fibroblast studies
  • Reduces melanin synthesis, supporting an even skin tone
  • Better transdermal penetration than standard L-ascorbic acid

Known concerns

  • Limited long-term human safety and irritation data outside manufacturer studies
  • Like other vitamin C derivatives may cause mild stinging in sensitive skin
  • No formal CIR or SCCS opinion yet published for this specific molecule

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related vitamin c derivatives

80
PALMITOYL 2-GLYCERYL ASCORBATE
Vitamin C derivative

Same plant / compound family

80
DISODIUM ISOSTEARYL SULFOSUCCINATE
Surfactant

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.