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Doxylamine (INN) and its salts

CAS 469-21-6
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Doxylamine (inn) And Its Salts is a cosmetic ingredient. Exercise caution due to limited available safety data.

Doxylamine is a first-generation antihistamine listed in EU Annex II (the list of substances prohibited in cosmetic products). It may not be used in cosmetic formulations at any concentration. The substance carries H302 (harmful if swallowed) hazard statements. Its inclusion in Annex II reflects the EU's precautionary approach to pharmacologically active ingredients that could pose systemic health risks.

Known concerns

  • EU Annex II banned — prohibited in all cosmetic products
  • Pharmacologically active substance with systemic effects
  • H302 acute oral toxicity hazard

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.