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Coumarin (brightening active)

ESCULETIN

CAS 305-01-1
60

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Esculetin is a plant-derived coumarin studied for skin brightening through tyrosinase inhibition and antioxidant action. It is a developing active that still needs careful formulation.

Skin benefits

  • Coumarin compound with tyrosinase-inhibiting brightening potential
  • Antioxidant action against free radicals in skin
  • Studied for hyperpigmentation and uneven tone
  • Active at relatively low concentrations

Known concerns

  • GHS H315 skin irritation, H319 serious eye irritation, H335 respiratory irritation
  • Coumarin scaffold raises phototoxicity and allergen questions
  • Limited formal CIR review for cosmetic use
  • Stability and dose still being established

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.