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ETHANOLAMINE THIOGLYCOLATE

CAS 126-97-6
28

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A hair-waving active restricted in EU cosmetics due to skin sensitization, corrosive potential, and formaldehyde release risk.

Ethanolamine thioglycolate is restricted under EU Annex III with references III/2a and III/61, indicating strict concentration limits and specific product-type restrictions. The compound is used in professional hair waving and depilatory products as a reducing agent that breaks disulfide bonds in keratin. It is a known skin sensitizer capable of causing allergic contact dermatitis, particularly in repeated exposure scenarios common among hairdressers. The thioglycolate moiety can also release formaldehyde upon degradation, triggering additional regulatory controls under EU formaldehyde-releasing substance requirements. Professional use only is recommended.

Known concerns

  • Skin sensitizer (EU Annex III III/2a, III/61)
  • Corrosive potential
  • Formaldehyde release on degradation
  • Restricted to professional use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.