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Solvent

ETHOXYDIGLYCOL

CAS 111-90-0
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A glycol ether solvent (diethylene glycol monoethyl ether) used to dissolve fragrance and actives. Generally safe at cosmetic levels but is a known penetration enhancer, so review surrounding ingredients.

Function

HUMECTANTSOLVENTPERFUMING

Skin benefits

  • Solubilizes fragrance and active ingredients
  • Improves penetration of water-insoluble actives
  • Helps form clear formulations

Known concerns

  • Penetration enhancer increases absorption of other ingredients
  • Mild eye and skin irritation possible at higher levels
  • Reproductive toxicity flags reviewed by SCCS at high oral doses

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

PC

PubChem

U.S. NIH compound data, GHS hazard codes and toxicity literature.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.