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ETHYL ACETOXYHEXANOATE

CAS 104986-28-9
70

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Ethyl Acetoxyhexanoate is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Ethyl acetoacetate of hexanoic acid (ethyl acetoacetate, ethyl 2-acetoxyhexanoate; CAS 104986-28-9) is a functionalized ester combining a beta-keto group with an acetoxy substituent. It is used in cosmetic fragrances as a specialty material, contributing fruity-spicy notes. There is limited publicly available toxicological data specifically on this compound. It is not listed in EU Annex II or III, indicating no current regulatory restriction. Its structural features (acetate ester and ketone) suggest moderate metabolic reactivity, and it is treated here as a fragrance material of acceptable but not extensively studied safety — earning a score in the 60–74 range.

Skin benefits

  • Fragrance material with fruity-spicy character
  • Used in specialty cosmetic fragrances

Known concerns

  • Limited published safety data
  • Acetate ester may hydrolyze to acetic acid on skin
  • Potential for mild irritation at high concentrations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.