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ETHYLHEXYL NEOPENTANOATE

CAS 16387-18-1
82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A lightweight, dry-feeling synthetic ester made from 2-ethylhexanol and pivalic acid, providing elegant texture in skincare formulations.

Ethylhexyl Neopentanoate is the ester of 2-ethylhexanol (a branched C8 alcohol) with pivalic acid (a branched C5 acid). The branched structure prevents close packing in the solid or liquid state, giving the ester a very low viscosity and dry, non-greasy skin feel. Functions as an emollient, skin-conditioning agent, and plasticizer in cosmetic formulations. It is an alternative to heavier straight-chain esters. 2-Ethylhexanol exposure is regulated but the ester form is considered safe in cosmetics at typical use levels. Not restricted in EU or US.

Skin benefits

  • Dry, non-greasy emolliency
  • Improves product aesthetics
  • Lightweight texture

Known concerns

  • Minor skin irritation at high concentrations only

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.