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ETHYLHEXYL NIACINAMIDE

CAS 541545-53-3
80

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

An oil-soluble ester of niacinamide designed for enhanced delivery into the skin barrier. Generally well-tolerated like its parent compound, though independent safety data on the ester remains limited.

Skin benefits

  • Lipid-soluble niacinamide derivative for improved skin penetration
  • Targets brightening and skin tone evenness
  • Less likely to cause flushing than niacin

Known concerns

  • Limited independent clinical data on this specific ester
  • Hydrolysis releases ethylhexanol which warrants impurity tracking
  • Newer ingredient with smaller safety dataset

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related actives

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.