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Synthetic colorant

Fluorescein, 2',4',5',7'-tetrabromo-4,5,6,7- tetrachloro-, disodium salt (CI 45410)

CAS 18472-87-2 Updated
50

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Phloxine B, a halogenated xanthene dye giving deep pink to red colors in lip and cheek products. Permitted in the EU under restrictions, but photoreactivity and halogen content put it in cautious territory.

Skin benefits

  • Bright pink/red xanthene dye used in lipsticks and color cosmetics
  • EU permitted colorant (CI 45410) within restricted uses
  • Provides intense staining at very low percentages
  • Long industrial track record as a cosmetic and food colorant

Known concerns

  • Contains brominated and chlorinated aromatic structure
  • Some studies suggest photo-reactivity and phototoxicity potential
  • PubChem flags eye damage (H318) and aquatic toxicity (H412) for related forms
  • Restricted from eye-area use in EU Annex IV

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Check your shelf

Find Fluorescein, 2',4',5',7'-tetrabromo-4,5,6,7- tetrachloro-, disodium salt (CI 45410) in your products.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.