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FLUORORESORCINOL THIAZOLYL CARBAMYL HYDROXYCYCLOBUTANE

43

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A cosmetic ingredient. Exercise caution due to limited available safety data.

Fluorination at the resorcinol position increases metabolic stability and lipophilicity, which may alter dermal absorption and sensitisation profile. The fluorine atom on an aromatic ring adjacent to phenolic hydroxyl groups can modulate the redox properties. Similar to other fluorophenol compounds, this may require additional environmental risk assessment under EU REACH due to organofluorine persistence concerns.

Skin benefits

  • Enhanced skin penetration from increased lipophilicity
  • Potential for sustained-release active delivery

Known concerns

  • Fluorination raises unexpected toxicity concerns
  • Resorcinol sensitisation risk compounded by altered absorption
  • No EU safety data on this specific fluorinated derivative

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.