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Phytoestrogen isoflavone

GENISTEIN GLUCOSIDE

CAS -
65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A glucose-conjugated form of the soy isoflavone genistein, used in anti-aging skincare as an antioxidant and skin-conditioning phytoestrogen. EU SCCS caps free genistein at 0.007% over endocrine-activity concerns.

Skin benefits

  • Phytoestrogen isoflavone with antioxidant activity
  • May support collagen synthesis and skin elasticity
  • Glucoside form has improved aqueous compatibility versus aglycone

Known concerns

  • SCCS 2022 opinion limits genistein in cosmetics to 0.007% due to endocrine-disruptor potential
  • Phytoestrogenic activity can interact with estrogen receptors
  • Conversion to free genistein in skin or gut means glucoside is treated similarly

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.