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GINSENOSIDES

CAS -
78

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A concentrated saponin fraction from Panax ginseng containing multiple ginsenoside types that stimulate collagen and reduce signs of aging.

Ginsenosides are triterpenoid saponins isolated from Panax ginseng (Asian ginseng) roots. The fraction contains multiple ginsenoside types (Rb1, Rb2, Rc, Rd, Re, Rg1, Rf) in varying ratios depending on extraction method. Ginsenosides Rg1 and Rb1 modulate aquaporin-3 expression and collagen synthesis in fibroblasts via the TGF-β/Smad pathway. They also inhibit MMP-1 upregulation from UV exposure. Overall adaptogenic and anti-aging. Minor risk of contact dermatitis reported in sensitised individuals.

Skin benefits

  • Anti-aging
  • Collagen stimulation
  • Anti-wrinkle
  • Anti-inflammatory

Known concerns

  • Mild contact allergen potential in susceptible individuals
  • May interact with corticosteroid pathways

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.