Glucocorticoids (Corticosteroids)
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Glucocorticoids (corticosteroids) is a cosmetic ingredient. Exercise caution due to limited available safety data.
Glucocorticoids such as hydrocortisone, betamethasone, and dexamethasone are pharmaceutical agents with potent anti-inflammatory and immunosuppressive properties. EU Regulation 1223/2009 Annex II prohibits their use in cosmetic products. Topical corticosteroid misuse in cosmetics can cause skin thinning (atrophy), striae formation, telangiectasia, perioral dermatitis, and systemic absorption leading to hypothalamic-pituitary-adrenal axis suppression. Long-term cosmetic use could lead to steroid dependence and rebound dermatitis upon discontinuation.
Known concerns
- EU Annex II banned - pharmaceutical agents
- Skin atrophy with prolonged use
- Systemic absorption and HPA axis suppression
- Steroid dependence and rebound dermatitis
- Perioral dermatitis risk
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.