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Glutaraldehyde (Pentane-1,5-dial)

CAS 111-30-8
42

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Glutaraldehyde (pentane-1,5-dial) is a cosmetic ingredient. Exercise caution due to limited available safety data.

Glutaraldehyde (pentane-1,5-dial) is a five-carbon dialdehyde used as a preservative in some cosmetic formulations. It is classified with extensive hazard statements including H301, H314 (severe skin burns), H317 (skin sensitization), H330, H334 (respiratory sensitization), H411 (aquatic toxicity), and others. EU Annex III restricts glutaraldehyde to a maximum of 0.1% in ready-to-use formulations. It is a known potent sensitizer requiring specific labeling under the Cosmetics Regulation.

Known concerns

  • Potent skin sensitizer (H317)
  • Respiratory sensitizer (H334)
  • Severe skin burns (H314)
  • Acute inhalation toxicity (H330)
  • EU Annex III restriction (max 0.1%)
  • Aquatic toxicity (H411)

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.