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Skin Conditioning

GLYCEROPHOSPHOINOSITOL ARGININE

74

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A phosphoinositol-arginine conjugate positioned as a skin-conditioning active. Limited public safety data — scored conservatively.

Glycerophosphoinositol arginine is a conjugate of glycerophosphoinositol (a phosphatidylinositol metabolite / cell-membrane breakdown product) with the amino acid arginine. Glycerophosphoinositol itself has been studied as an endogenous anti-inflammatory mediator in immune-cell biology. In cosmetics this INCI is used as a skin-conditioning agent. EU CosIng lists it for skin-conditioning function; no Annex II/III restrictions and no formal CIR/SCCS review. Cosmetic safety dossier is limited, so scoring defaults to mid-yellow.

Function

SKIN PROTECTING

Skin benefits

  • Inositol-phospholipid derivative for skin conditioning
  • Arginine pairing supports humectant behaviour
  • Anti-inflammatory potential reported

Known concerns

  • Limited public cosmetic data
  • Niche ingredient with proprietary dossier
  • Unclear high-concentration tolerance

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related skin conditionings

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.