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Skin Conditioning

GLYCERYL GLYCYRRHETINATE

CAS 108916-85-4 Updated
80

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A glycerol ester of glycyrrhetinic acid (the active part of licorice) — a well-tolerated soothing and anti-inflammatory active. Common in calming and post-treatment cosmetics with a strong tradition of safe use.

Function

SURFACTANT - EMULSIFYING

Skin benefits

  • Skin-soothing and anti-inflammatory action from glycyrrhetinate
  • Improved penetration over the parent triterpenoid
  • Useful in sensitive-skin and post-procedure formulations

Known concerns

  • Pseudohyperaldosteronism only at high systemic exposures
  • Sourcing variability in licorice extracts
  • Possible mild plant-allergy cross-reactions

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.