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Skin Conditioning

GLYCYRRHETINIC ACID

CAS 471-53-4
80

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Glycyrrhetinic acid (from licorice root) — strong skin-soothing and anti-redness ingredient. Topical cosmetic use is well below the levels that raise concern in oral/systemic contexts.

Function

SKIN CONDITIONING

Skin benefits

  • Anti-inflammatory and skin soothing
  • Reduces redness
  • Supports compromised skin
  • Mild brightening

Known concerns

  • High systemic intake linked to mineralocorticoid effects (oral)
  • Cosmetic levels well below concern

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

PC

PubChem

U.S. NIH compound data, GHS hazard codes and toxicity literature.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.