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Soothing botanical derivative

GLYCYRRHETINIC GLUCURONIDE

72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A licorice-derived sugar-conjugated form of glycyrrhetinic acid used as a skin-soothing conditioning agent. Improves water solubility while keeping the calming, anti-redness profile of licorice extracts.

Skin benefits

  • Soothes skin and calms visible redness
  • Antioxidant properties from licorice-derived glycyrrhetinic backbone
  • Skin conditioning at typical cosmetic use levels
  • Improved water solubility versus parent glycyrrhetinic acid

Known concerns

  • Limited published toxicology specific to the glucuronide conjugate
  • Parent glycyrrhetinic acid has theoretical mineralocorticoid activity at high systemic exposure
  • No dedicated SCCS or CIR review of this exact derivative

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.