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GUAIACOL ACETATE

CAS 613-70-7
60

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An aromatic acetate ester of guaiacol providing a sweet, vanilla-like scent; used in fragrances with no EU restrictions but may act as a mild sensitizer in some individuals.

Guaiacol acetate (o-methoxyphenyl acetate) is an aromatic ester derived from guaiacol, exhibiting a sweet, slightly smoky, vanilla-like odor. While guaiacol itself is used in food and pharmaceuticals, the acetate derivative has limited published toxicological data. CosIng shows no EU regulatory restrictions. In common with many phenolic and aromatic compounds, mild skin sensitization is theoretically possible at high concentrations.

Skin benefits

  • Vanilla-sweet fragrance component

Known concerns

  • Theoretical skin sensitization potential at high concentrations
  • Limited public toxicological data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.