Skip to content

Guanethidine monosulfate

CAS 645-43-2
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Guanethidine Monosulfate is a cosmetic ingredient. Exercise caution due to limited available safety data.

Guanethidine monosulfate is an antihypertensive agent that acts as a false neurotransmitter and depletes norepinephrine from sympathetic nerve terminals. With acute oral toxicity (H302) and significant pharmacological activity on the cardiovascular system, it is classified as a prescription-only medicine and is not permitted in cosmetic formulations. Not listed in EU approved cosmetic databases.

Known concerns

  • Acute oral toxicity (H302)
  • Cardiovascular pharmacological effects
  • Antihypertensive drug
  • Not approved for cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Check your shelf

Find Guanethidine monosulfate in your products.

Scan any cosmetic product with LuxSense to see if it contains Guanethidine monosulfate and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.