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Guanethidine monosulfate

CAS 645-43-2
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Guanethidine Monosulfate is a cosmetic ingredient. Exercise caution due to limited available safety data.

Guanethidine monosulfate is an antihypertensive agent that acts as a false neurotransmitter and depletes norepinephrine from sympathetic nerve terminals. With acute oral toxicity (H302) and significant pharmacological activity on the cardiovascular system, it is classified as a prescription-only medicine and is not permitted in cosmetic formulations. Not listed in EU approved cosmetic databases.

Known concerns

  • Acute oral toxicity (H302)
  • Cardiovascular pharmacological effects
  • Antihypertensive drug
  • Not approved for cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.