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pH Adjuster

GUANIDINE HCL

CAS 50-01-1 Updated
24

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A strongly corrosive salt used industrially and as a protein denaturant. Carries severe GHS hazards; not appropriate for leave-on cosmetics, only carefully formulated rinse-off systems.

Function

BUFFERING

Skin benefits

  • pH adjuster (rinse-off only)
  • Strong protein denaturant

Known concerns

  • Causes severe skin burns and eye damage (GHS H314)
  • Toxic if swallowed/inhaled (H301/H311/H331)
  • Causes damage to organs (H370)
  • Highly corrosive — never for leave-on cosmetics
  • Strict raw-material handling required

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related ph adjusters

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.