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GUANYLCYSTAMINE HBR

CAS 15086-17-6
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Guanylcystamine Hbr is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

The hydrobromide salt of a guanidylcysteineamine derivative - a synthetic cysteine and guanidine hybrid. The guanidine moiety (like arginine) is positively charged at physiological pH, conferring substantivity to negatively charged keratin. Used as a hair conditioning active with some in vitro evidence of protein substantivity. Limited published safety data specific to cosmetic use; the compound is not widely used in consumer products. The HBr salt form introduces bromide ion considerations at high concentrations. No specific EU Annex restriction identified.

Skin benefits

  • Substantive to damaged hair protein
  • Conditions and strengthens hair
  • May reduce hair breakage

Known concerns

  • Limited cosmetic safety data available
  • Bromide ion release at high concentrations may cause irritation
  • Not well-studied for long-term topical use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.